Endocrine Abstracts

The aim of this study was to verify if genetic factors influence the short- and long-term therapeutic response to estroprogestagen (EP) therapy implemented in girls with functional hypothalamic amenorrhea (FHA) in order to improve their bone mineral density (BMD). The study included 78 FHA girls who underwent a 4-year sequential EP therapy with 17β-estradiol and didrogesterone. Changes in the lumbar spine BMD were determined at the end of the therapy and 6 years after its...